PPP1R12B
Description
The PPP1R12B (protein phosphatase 1 regulatory subunit 12B) is a protein-coding gene located on chromosome 1.
PPP1R12B is a gene that encodes for the protein phosphatase 1 regulatory subunit 12B, an enzyme involved in regulating myosin phosphatase activity. It plays a crucial role in muscle contraction by enhancing the dephosphorylation of myosin, a process facilitated by its binding to the myosin binding subunit (MBS). PPP1R12B exists in multiple isoforms, with some binding to other regulatory subunits like PPP1R12A. Additionally, it interacts with Interleukin 16, highlighting its multifaceted roles in cellular processes.
PPP1R12B is also known as MYPT2, PP1bp55.
