PPIL4


Description

The PPIL4 (peptidylprolyl isomerase like 4) is a protein-coding gene located on chromosome 6.

PPIL4 is a human gene encoding an enzyme belonging to the cyclophilin family of peptidylprolyl isomerases. Cyclophilins play crucial roles in protein folding, immunosuppression by cyclosporin A, and HIV-1 virion infection.

PPIL4, also known as Cyclophilin-like protein PPIL4 or Rotamase PPIL4, is a peptidyl-prolyl cis-trans isomerase (PPIase) that accelerates protein folding. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides, aiding in the proper conformation of proteins.

PPIL4 is also known as HDCME13P.

Associated Diseases



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