POLR2J4
Description
The POLR2J4 (RNA polymerase II subunit J4 (pseudogene)) is a pseudo gene located on chromosome 7.
POLR2J4 is a protein-coding gene located on chromosome 19. It encodes a protein that is a subunit of RNA polymerase II (Pol II), a multi-subunit enzyme responsible for transcribing DNA into RNA. POLR2J4 interacts with the C-terminal domain (CTD) of the largest subunit of Pol II, suggesting a role in transcription initiation and elongation. Its precise function within the Pol II complex is not fully elucidated, but its interaction with the CTD points to its involvement in regulating transcription processes. In addition to transcription, POLR2J4 has been associated with DNA damage response pathways, suggesting a broader role in maintaining genomic integrity.
POLR2J4 is a component of the RNA polymerase II (Pol II) complex, a crucial enzyme responsible for transcribing DNA into RNA. It specifically interacts with the C-terminal domain (CTD) of the largest subunit of Pol II, playing a role in transcription initiation and elongation. The precise function of POLR2J4 within the Pol II complex is still under investigation, but its association with the CTD suggests involvement in regulating transcription processes. In addition to its role in transcription, POLR2J4 has been linked to DNA damage response pathways. This connection indicates a broader role in maintaining genomic integrity.
POLR2J4 is also known as RPB11-phi.
