POLR1E
Description
The POLR1E (RNA polymerase I subunit E) is a protein-coding gene located on chromosome 9.
The POLR1E gene encodes the DNA-directed RNA polymerase I subunit RPA49, an enzyme that synthesizes ribosomal RNA precursors using the four ribonucleoside triphosphates as substrates.
The POLR1E gene encodes a protein that is a component of RNA polymerase I (Pol I), a DNA-dependent RNA polymerase that synthesizes ribosomal RNA precursors using the four ribonucleoside triphosphates as substrates. This protein appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF.
POLR1E is also known as A49, PAF53, PRAF1, RPA49.
