PIR
Description
The PIR (pirin) is a protein-coding gene located on chromosome X.
PIR, or Pir, can refer to the human gene PIR, which encodes the protein Pirin.
PIR acts as a transcriptional coregulator of NF-kappa-B, enhancing the binding of NF-kappa-B proteins to target kappa-B genes in a manner dependent on redox state. PIR may be crucial for the effective terminal myeloid maturation of hematopoietic cells. It possesses quercetin 2,3-dioxygenase activity in vitro.
PIR is also known as -.
