PGBD3
Description
The PGBD3 (piggyBac transposable element derived 3) is a protein-coding gene located on chromosome 10.
PGBD3 is a protein-coding gene located on chromosome 19. It encodes a protein that contains a poly(ADP-ribose) glycohydrolase (PARG) domain. This protein is involved in DNA repair and regulation of gene expression.
PGBD3, also known as Poly(ADP-ribose) glycohydrolase domain-containing protein 3, plays a crucial role in DNA repair and regulation of gene expression. This protein functions as a PARG (poly(ADP-ribose) glycohydrolase) enzyme, which is responsible for removing poly(ADP-ribose) (PAR) chains from target proteins. PARylation is a post-translational modification that is crucial for DNA damage response and other cellular processes. PGBD3's PARG activity contributes to the restoration of cellular homeostasis by modulating PAR levels and enabling efficient DNA repair. Additionally, PGBD3 may be involved in regulating gene transcription by interacting with DNA-binding proteins and influencing chromatin structure.
PGBD3 is also known as -.
