PDZD11
Description
The PDZD11 (PDZ domain containing 11) is a protein-coding gene located on chromosome X.
PDZD11 is a protein encoded by the PDZD11 gene in humans.
PDZD11 facilitates the attachment of ADAM10 to zonula adherens by interacting with PLEKHA7. This interaction is crucial for PLEKHA7 to bind to TSPAN33, a protein that binds to ADAM10.
PDZD11 is also known as AIPP1, PDZK11, PISP.
Associated Diseases
- endometrial cancer
- cancer
- Alzheimer disease
- uterine corpus endometrial carcinoma
- parkinsonism-dystonia, infantile
