PDE1C
Description
The PDE1C (phosphodiesterase 1C) is a protein-coding gene located on chromosome 7.
PDE1C is a human gene that encodes calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C, an enzyme involved in the regulation of cellular signaling.
PDE1C is a calmodulin-dependent cyclic nucleotide phosphodiesterase that hydrolyzes both cAMP and cGMP, which are important signaling molecules in various cellular processes. It plays a role in regulating the amplitude and duration of cAMP signals in sensory cilia, contributing to odorant detection and action potential generation. PDE1C also regulates smooth muscle cell proliferation and potentially the stability of growth factor receptors like PDGFRB.
PDE1C is also known as DFNA74, Hcam3, cam-PDE 1C, hCam-3.
