GYS2 : glycogen synthase 2
Description
The GYS2 gene encodes glycogen synthase 2, a key enzyme responsible for glycogen synthesis in skeletal muscle. Glycogen, a branched polymer of glucose, serves as a readily available energy source for muscle contraction. GYS2 is highly expressed in skeletal muscle and plays a crucial role in maintaining muscle glycogen stores, which are essential for sustained physical activity. It is regulated by various factors, including insulin, glucose, and physical activity. Mutations in the GYS2 gene can lead to glycogen storage disorders, characterized by impaired glycogen metabolism and muscle weakness.
Associated Diseases
Did you know?
GYS2 activity is increased during exercise, allowing muscles to replenish glycogen stores efficiently.
