CD79A

Description

The CD79A gene, also known as mb-1, encodes a transmembrane protein that forms a complex with CD79B to create the B cell receptor (BCR) complex. This complex is essential for B cell development, activation, and signaling. Upon antigen binding, the BCR transmits signals into the cell, triggering downstream signaling pathways that lead to B cell proliferation, differentiation, and antibody production. Mutations or defects in the CD79A gene can disrupt B cell function, leading to various immune disorders.

Associated Diseases

• Chronic Lymphocytic Leukemia (CLL)
• B-Cell Lymphoma
• Common Variable Immunodeficiency (CVID)
• Agammaglobulinemia
• Autoimmune Disorders

Did you know?

CD79A is expressed exclusively in B cells, making it a valuable marker for identifying and targeting these cells in both normal and diseased states.