CCN6 : cellular communication network factor 6
Description
The CCN6 (cellular communication network factor 6) is a protein-coding gene located on chromosome 6.
The CCN6 gene provides instructions for making a protein that appears to be involved in bone growth and the maintenance of cartilage. The exact function of the CCN6 protein is not fully understood, but it is known to be part of a family of proteins that are involved in the growth and maintenance of connective tissues, such as bone, cartilage, and blood vessels. The CCN6 protein is produced by cells called chondrocytes, which are responsible for creating and maintaining cartilage, and it is associated with the production of certain proteins that make up cartilage. However, its role in their production is not entirely clear. CCN6 may also play a role in regulating signaling pathways involved in the development of cartilage and bone and may help control the breakdown of cartilage components.
CCN6 plays a role in mitochondrial electron transport and mitochondrial respiration, which in turn may contribute to normal postnatal skeletal growth and cartilage homeostasis.
CCN6 is also known as LIBC, PPAC, PPD, PPRD, WISP-3, WISP3.
Associated Diseases
- Arthropathy, progressive pseudorheumatoid, of childhood
- Progressive pseudorheumatoid arthropathy of childhood
- Juvenile idiopathic arthritis
- Progressive pseudorheumatoid dysplasia
