C4B

Description

The C4B gene provides instructions for making a protein called complement component 4B. This protein is part of the complement system, a complex network of proteins that plays a crucial role in the immune response. The complement system helps eliminate pathogens and damaged cells, and it plays a role in inflammation. C4B is a key component of the classical pathway of complement activation, which is triggered by the binding of antibodies to antigens.

Associated Diseases

• Systemic lupus erythematosus (SLE)
• Rheumatoid arthritis
• Multiple sclerosis
• Type 1 diabetes
• Psoriasis
• Inflammatory bowel disease
• Alzheimer‘s disease
• Schizophrenia
• Cancer

Did you know?

C4B is one of the most polymorphic genes in the human genome, meaning that there are many different versions of the gene in the population. These variations can influence the function of the complement system and may be associated with different disease risks.