OR2M3


Description

The OR2M3 (olfactory receptor family 2 subfamily M member 3) is a protein-coding gene located on chromosome 1.

Olfactory receptor 2M3 is a protein that in humans is encoded by the OR2M3 gene. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. OR2M3 has a copper binding pocket. 3-Mercapto-2-methylpentan-1-ol, a chemical associated with the characteristic smell of raw onions, is a known ligand for OR2M3.

Odorant receptor.

OR2M3 is also known as OR1-54, OR2M3P, OR2M6, OST003.

Associated Diseases



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