OR1E1
Description
The OR1E1 (olfactory receptor family 1 subfamily E member 1) is a protein-coding gene located on chromosome 17.
Olfactory receptor 1E1 is a protein that in humans is encoded by the OR1E1 gene. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
Odorant receptor.
OR1E1 is also known as HGM071, OR13-66, OR17-2, OR17-32, OR1E5, OR1E6, OR1E8P, OR1E9P, OST547.
Associated Diseases
- Lynch syndrome
- colorectal cancer, susceptibility to, 3
- Hirschsprung disease
- familial adenomatous polyposis 2
- AXIN2-related attenuated familial adenomatous polyposis
- 46,XY complete gonadal dysgenesis
- anal canal carcinoma
- hereditary mixed polyposis syndrome
- 46,XX ovotesticular disorder of sex development
- Lynch syndrome 8
- chronic intestinal pseudoobstruction
- testicular agenesis
- 46,XY disorder of sex development due to 5-alpha-reductase 2 deficiency
- Leydig cell hypoplasia
- 46,XX testicular disorder of sex development
- colorectal cancer, susceptibility to, 10
