UNC45B

• SHARE NOW |
• Tweet Opens in a new window.
• Pin it Opens in a new window.
• Share Opens in a new window.
• Share Opens in a new window.
• Email Opens in a new window.

---

Description

The UNC45B (unc-45 myosin chaperone B) is a protein-coding gene located on chromosome 17.

UNC45B acts as a co-chaperone for HSP90, essential for the correct folding of the myosin motor domain. It plays a crucial role in sarcomere formation during muscle cell development and is vital for normal early lens development.

UNC45B is also known as CMYA4, CTRCT43, MFM11, SMUNC45, UNC-45B, UNC45.

Associated Diseases

• Cataract 43
• Myofibrillar myopathy 11