TUBGCP4

Description

TUBGCP4, also known as Tubulin Gamma Complex Protein 4, is a protein-coding gene that plays a crucial role in microtubule dynamics, a fundamental process essential for cell division, intracellular transport, and cellular organization. The TUBGCP4 gene encodes a protein that interacts with tubulin, the building block of microtubules, and influences their assembly, stability, and function. These microtubules are dynamic structures that constantly undergo polymerization and depolymerization, enabling cells to divide and maintain their shape. Mutations in the TUBGCP4 gene can disrupt this intricate process, leading to a range of cellular defects and potentially contributing to various diseases.

Associated Diseases

• Microcephaly
• Microcephaly and chorioretinopathy, autosomal recessive, 3

Did you know?

TUBGCP4 is expressed predominantly in the brain, particularly in regions responsible for neuronal development and function. This suggests a significant role of this gene in brain development and neurological processes.