SLC38A8
Description
The SLC38A8 gene encodes a protein known as solute carrier family 38 member 8, a vital component of the amino acid transport system within cells. SLC38A8 facilitates the uptake of specific amino acids, including glutamine, asparagine, and histidine, into cells. These amino acids are essential building blocks for protein synthesis, cellular energy production, and various metabolic processes. The gene‘s proper functioning is crucial for maintaining cellular homeostasis and overall organismal health.
Associated Diseases
- Cancer: Altered SLC38A8 expression has been linked to tumor growth and metastasis in various cancers, including breast cancer, colorectal cancer, and lung cancer.
- Neurological Disorders: Dysregulation of SLC38A8 function has been implicated in neurodevelopmental disorders and neurodegenerative diseases, such as autism spectrum disorder and Alzheimer‘s disease.
- Metabolic Disorders: SLC38A8 plays a role in regulating amino acid metabolism, and its dysfunction can contribute to metabolic disorders like diabetes and obesity.
Did you know?
SLC38A8 is highly expressed in the brain, suggesting a critical role in neuronal function and development.
