PEX11B

Description

The PEX11B (peroxisomal biogenesis factor 11 beta) is a protein-coding gene located on chromosome 1.

Peroxisomal membrane protein 11B is a protein that in humans is encoded by the PEX11B gene. It is involved in the regulation of peroxisome abundance.

== Interactions == PEX11B has been shown to interact with PEX19.

PEX11B is involved in peroxisome proliferation (PubMed:9792670). It may regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane (PubMed:12618434). It promotes membrane protrusion and elongation on the peroxisomal surface (PubMed:20826455).

PEX11B is also known as PEX11-BETA, PEX11beta, PEX14B.

Associated Diseases

• Zellweger syndrome
• Infantile Refsum disease
• Peroxisome biogenesis disorder 14B
• Neonatal adrenoleukodystrophy