GFER
Description
The GFER gene (Glutathione Ferredoxin Reductase) encodes a critical enzyme involved in iron metabolism. It catalyzes the reduction of oxidized glutathione, a vital antioxidant, using electrons from ferredoxin. This process is essential for maintaining cellular iron homeostasis, protecting against oxidative stress, and ensuring efficient iron utilization. GFER‘s role in iron metabolism is tightly linked to its interaction with other proteins involved in iron transport and regulation, making it a crucial component of the intricate cellular machinery managing iron levels.
Associated Diseases
Did you know?
GFER is highly expressed in tissues with high iron requirements, such as the liver, spleen, and bone marrow.
