FTL : ferritin light chain
Description
The FTL (ferritin light chain) is a protein-coding gene located on chromosome 19.
The FTL gene instructs the production of the ferritin light chain, a subunit of ferritin, a protein composed of 24 subunits arranged in a hollow sphere. Ferritin stores and releases iron in cells, holding up to 4,500 iron atoms within its structure. Ferritin's storage capacity regulates iron levels in cells and tissues. Iron is essential for red blood cell production.
FTL is also known as FTL1, LFTD, NBIA3.
Associated Diseases
- Neurodegeneration with brain iron accumulation 3
- L-ferritin deficiency, dominant and recessive
- Neuroferritinopathy
- Genetic hyperferritinemia without iron overload
- Hereditary hyperferritinemia-cataract syndrome
- Hyperferritinemia with or without cataract
- Hyperferritinemia-cataract syndrome
