DTNBP1

Description

The DTNBP1 gene, also known as dysbindin, plays a crucial role in brain development and function. It encodes a protein that is involved in various cellular processes, including vesicle trafficking, signal transduction, and neuronal survival. DTNBP1 is expressed throughout the brain, particularly in regions associated with learning, memory, and cognition. Dysregulation of DTNBP1 has been implicated in several neurodevelopmental and neuropsychiatric disorders, highlighting its importance in maintaining brain health.

Associated Diseases

• Schizophrenia
• Bipolar disorder
• Major depressive disorder
• Attention-deficit/hyperactivity disorder (ADHD)
• Autism spectrum disorder
• Alzheimer‘s disease
• Parkinson‘s disease

Did you know?

DTNBP1 gene was originally identified as a candidate gene for schizophrenia in a genome-wide association study.