OPALIN
Description
The OPALIN (oligodendrocytic myelin paranodal and inner loop protein) is a protein-coding gene located on chromosome 10.
Opalin is a protein encoded by the OPALIN gene in humans.
Opalin is a central nervous system-specific myelin protein that plays a role in the formation of myelin sheaths around nerve fibers. It increases the expression of myelin genes during oligodendrocyte differentiation, which is the process by which oligodendrocytes mature and produce myelin. Opalin also promotes the terminal differentiation of oligodendrocytes, the final stage of their development.
OPALIN is also known as HTMP10, TMEM10, TMP10.
Associated Diseases
- multiple sclerosis
- demyelinating disease
- hereditary spastic paraplegia
- Huntington disease
- Parkinson disease
