OLAH
Description
The OLAH (oleoyl-ACP hydrolase) is a protein-coding gene located on chromosome 10.
OLAH plays a role in releasing free fatty acids from fatty acid synthase (FASN). It can act on a variety of fatty acid substrates, generating free fatty acids with carbon chains ranging from 10 to 16 atoms long (C10-C16).
OLAH is also known as AURA1, SAST, TE2, THEDC1.
Associated Diseases
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome
- alpha thalassemia-intellectual disability syndrome type 1
- hemoglobin D disease
- delta-beta-thalassemia
- hemoglobin E-beta-thalassemia syndrome
- hemolytic anemia due to adenylate kinase deficiency
- Heinz body anemia
- alpha-thalassemia-myelodysplastic syndrome
- hemoglobin C-beta-thalassemia syndrome
- dominant beta-thalassemia
- hemoglobin E disease
- monosomy 7 myelodysplasia and leukemia syndrome 1
- hemoglobin H disease
