ODF3B
Osteogenesis Imperfecta (OI): A Comprehensive Guide
Description:
Osteogenesis imperfecta (OI) is a rare genetic disorder characterized by weakened and brittle bones. People with OI suffer frequent fractures, even from minor injuries or everyday activities. The severity of the condition varies widely, ranging from mild to severe forms.
Associated Diseases:
OI is often associated with other medical conditions, including:
- Dentinogenesis imperfecta: This condition causes teeth to be weak and discolored.
- Hearing loss: OI can affect the inner ear, leading to conductive or sensorineural hearing loss.
- Eye problems: People with OI may experience nearsightedness, blue sclera (white portion of the eye appearing blue), and other vision issues.
- Scoliosis: OI can cause the spine to curve abnormally, known as scoliosis.
- Joint dislocations: Weakened ligaments and joints can lead to recurrent dislocations.
Did you Know ?
According to the National Institutes of Health, the prevalence of OI is estimated to be between 1 in 20,000 and 1 in 50,000 people worldwide.
