NPBWR2
Neurological Paraneoplastic Brain-Retina Syndrome (NPBR2)
Description:
Neurological paraneoplastic brain-retina syndrome (NPBR2) is a rare neurological condition that affects both the brain and the eyes. It is caused by the immune system attacking the body's own brain and retinal cells, leading to a range of neurological symptoms.
Associated Diseases:
NPBR2 is most commonly associated with cancer, particularly lung cancer, breast cancer, and hematological malignancies such as lymphoma. In some cases, the development of NPBR2 may precede the diagnosis of cancer, making it a potential early indicator.
Symptoms:
The symptoms of NPBR2 can vary depending on the severity of the condition. Common neurological symptoms include:
- Seizures
- Encephalopathy (confusion, impaired memory)
- Visual disturbances (blurred vision, double vision, night blindness)
- Cerebellar ataxia (imbalance, uncoordinated movements)
- Headache
- Weakness
Did you Know ?
NPBR2 is a rare condition, affecting less than 1 in 1 million people. However, the incidence of NPBR2 is increasing, potentially due to improved cancer screening and survival rates.
