NOXRED1
Description
The NOXRED1 (NADP dependent oxidoreductase domain containing 1) is a protein-coding gene located on chromosome 14.
NOXRED1, also known as Chromosome 14 Open Reading Frame 148 (c14orf148), is a human gene located on chromosome 14 at position 14q24.3. It encodes a protein predicted to be involved in pyrroline-5-carboxylate reductase activity, a crucial step in the L-proline biosynthesis pathway. NOXRED1 is expressed in various tissues, including testes, thyroid, skin, small intestine, brain, kidney, and colon, albeit at relatively low levels. The gene spans 29,502 bases and consists of 9 exons and 8 introns. It is located on the minus strand of chromosome 14. NOXRED1's gene neighborhood includes TMED8, SAMD15, VIPAS39, and AHSA1. There are three known mRNA isoforms of NOXRED1, with the primary isoform being 2324 bases long and composed of 6 exons.
NOXRED1 is also known as C14orf148.
