NOX5

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Description

The NOX5 (NADPH oxidase 5) is a protein-coding gene located on chromosome 15.

NOX5 is a protein encoded by the NOX5 gene. It is a novel NADPH oxidase that generates superoxide. NOX5 interacts with c-abl, and superoxide production leads to phosphorylation of c-abl. Inhibition of c-abl kinase activity inhibits Nox5 superoxide production.

NOX5 is also known as -.

Associated Diseases

• COVID-19
• Hirschsprung disease
• cancer
• type 2 diabetes mellitus
• ventricular septal defect