NEXN
Description
The NEXN (nexilin F-actin binding protein) is a protein-coding gene located on chromosome 1.
NEXN plays a crucial role in regulating cell migration by interacting with the actin cytoskeleton. It is essential for maintaining the integrity of the Z line and sarcomere, structures vital for muscle function. These roles have been observed in studies published in PubMed IDs 12053183, 15823560, and 19881492.
NEXN is also known as CMH20, NELIN.
Associated Diseases
- Cardiomyopathy, familial hypertrophic, 20
- Familial isolated dilated cardiomyopathy
- Cardiomyopathy, dilated, 1cc
