NEUROD4
Description
The NEUROD4 (neuronal differentiation 4) is a protein-coding gene located on chromosome 12.
NeuroD4 likely functions as a transcriptional activator, playing a key role in neuronal differentiation. It is particularly important for controlling the development of amacrine cells, a type of neuron in the retina.
NEUROD4 is also known as ATH-3, ATH3, Atoh3, MATH-3, MATH3, bHLHa4.
Associated Diseases
- infantile-onset autosomal recessive nonprogressive cerebellar ataxia
- spinocerebellar ataxia type 35
- spinocerebellar ataxia type 37
- spinocerebellar ataxia type 5
- hereditary spastic paraplegia 30
- spinocerebellar ataxia type 30
- spinocerebellar ataxia type 31
- spinocerebellar ataxia type 26
- spinocerebellar ataxia type 15/16
- spinocerebellar ataxia type 29
- spinocerebellar ataxia type 12
- spinocerebellar ataxia type 18
- spinocerebellar ataxia type 19/22
