CFHR5 : complement factor H related 5
Description
The CFHR5 (complement factor H related 5) is a protein-coding gene located on chromosome 1.
The CFHR5 gene provides instructions for making a protein called complement factor H-related 5. Its precise function is unknown, but its structure is similar to complement factor H, which regulates the complement system. The complement system is a group of proteins that fight foreign invaders, trigger inflammation, and clear debris. CFHR5 likely plays a role in controlling the complement system, potentially by preventing its activation when unnecessary.
CFHR5 plays a role in regulating the complement system. It forms dimers that bind to complement fragments attached to tissues, effectively competing with the normal complement inhibitor CFH.
CFHR5 is also known as CFHL5, CFHR5D, FHR-5, FHR5.
