SI
Description
The SI gene, encoding the signaling lymphocytic activation molecule (SLAM), plays a pivotal role in the regulation of immune responses. It acts as a receptor on immune cells, triggering intracellular signaling pathways that influence cell activation, differentiation, and cytokine production. This intricate dance of molecular interactions ensures appropriate immune responses, balancing immune defense against self-harm.
Associated Diseases
- Autoimmune diseases (e.g., systemic lupus erythematosus, rheumatoid arthritis)
- Infectious diseases (e.g., HIV infection, viral hepatitis)
- Cancer (e.g., leukemia, lymphoma)
- Allergies and asthma
Did you know?
The SI gene is highly polymorphic, meaning it exists in many variations within the human population. These variations can influence the strength and specificity of immune responses.
