NUP160

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Description

NUP160, also known as nucleoporin 160, is a vital component of the nuclear pore complex (NPC), the intricate gateway controlling the movement of molecules between the nucleus and cytoplasm. This protein acts as a scaffold, providing structural support and contributing to the complex regulation of nucleocytoplasmic transport. NUP160 interacts with numerous other proteins involved in transport, ensuring the selective and efficient movement of essential molecules, including messenger RNA, ribosomal subunits, and regulatory proteins.

Associated Diseases

• Neurodevelopmental disorders
• Intellectual disability
• Cerebral palsy
• Microcephaly
• Spinal muscular atrophy

Did you know?

The NUP160 gene is highly conserved across species, highlighting its fundamental role in cellular function.