IFT27

Description

The IFT27 gene provides instructions for making a protein that is essential for the proper assembly and function of cilia. Cilia are tiny, hair-like structures found on the surface of many cells in the body. They play crucial roles in various cellular processes, including sensing the environment, moving fluids, and cell signaling. Mutations in the IFT27 gene can disrupt ciliary function, leading to a range of health problems.

Associated Diseases

• Bardet-Biedl syndrome
• Sensenbrenner syndrome
• Joubert syndrome
• Meckel-Gruber syndrome
• Orofaciodigital syndrome type VI
• Nephronophthisis
• Alstrom syndrome
• Senior-Løken syndrome

Did you know?

IFT27 is part of a complex machinery called the intraflagellar transport (IFT) system, which transports essential building blocks for cilia assembly.