CD2AP

Description

CD2AP (CD2-associated protein) is a multifaceted adaptor protein involved in a wide range of cellular processes, including cell adhesion, cytoskeletal organization, and signal transduction. It plays a crucial role in mediating interactions between various proteins, forming multi-protein complexes that regulate diverse cellular functions. CD2AP‘s ability to interact with multiple partners allows it to act as a molecular scaffold, orchestrating complex signaling pathways and influencing cell behavior.

Associated Diseases

• Podocyte injury and kidney disease (e.g., focal segmental glomerulosclerosis, nephrotic syndrome)
• Diabetic nephropathy
• Cancer (e.g., breast cancer, prostate cancer, melanoma)
• Neurological disorders (e.g., Alzheimer‘s disease)
• Inflammatory bowel disease

Did you know?

Mutations in the CD2AP gene are associated with an increased risk of developing focal segmental glomerulosclerosis (FSGS), a kidney disease that can lead to kidney failure.