AGPAT2 : 1-acylglycerol-3-phosphate O-acyltransferase 2
Description
The AGPAT2 (1-acylglycerol-3-phosphate O-acyltransferase 2) is a protein-coding gene located on chromosome 9.
The AGPAT2 gene provides instructions for making an enzyme that is essential for the production of fats (lipids) in many cells and tissues. It plays a crucial role in the growth and development of adipocytes, which store fats for energy. This enzyme is involved in a chemical pathway that produces glycerophospholipids, the main component of cell membranes, and triacylglycerols, fat molecules stored for energy. AGPAT2 specifically facilitates the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a crucial step in the production of both glycerophospholipids and triacylglycerols.
AGPAT2 is also known as 1-AGPAT2, BSCL, BSCL1, LPAAB, LPAAT-beta, LPLAT2.
