ACE
Description
The angiotensin-converting enzyme (ACE) gene plays a crucial role in regulating blood pressure by influencing the renin-angiotensin-aldosterone system (RAAS). This system controls blood volume and pressure through the production and regulation of angiotensin II, a potent vasoconstrictor. The ACE gene encodes for the ACE enzyme, which converts angiotensin I to angiotensin II. Variations in the ACE gene can affect enzyme activity, leading to different levels of angiotensin II production and ultimately influencing blood pressure.
Associated Diseases
- Hypertension (high blood pressure)
- Cardiovascular disease (heart disease, stroke)
- Kidney disease
- Preeclampsia (a pregnancy complication)
- Diabetes
- Asthma
Did you know?
The ACE gene is located on chromosome 17 and has been linked to athletic performance, particularly in endurance sports.
