NCR1

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Description

The NCR1 (natural cytotoxicity triggering receptor 1) is a protein-coding gene located on chromosome 19.

Natural cytotoxicity triggering receptor 1 (NCR1) is a protein encoded by the NCR1 gene in humans. It is also known as CD335, NKP46, NKp46, NK-p46, and LY94.

NCR1, also known as NKp46, is a receptor involved in activating natural killer (NK) cells, which are important for killing tumor cells. It enhances the efficiency of activated NK cells in eliminating tumor cells.

NCR1 is also known as CD335, LY94, NK-p46, NKP46.

Associated Diseases

• Wiskott-Aldrich syndrome
• autosomal recessive primary immunodeficiency with defective spontaneous natural killer cell cytotoxicity
• immunodeficiency 18
• common variable immunodeficiency
• isolated agammaglobulinemia
• severe combined immunodeficiency due to CTPS1 deficiency
• severe combined immunodeficiency due to IKK2 deficiency
• severe combined immunodeficiency due to CARD11 deficiency
• combined immunodeficiency with skin granulomas
• immunodeficiency, common variable, 4
• agammaglobulinemia 7, autosomal recessive
• breast cancer