MT2A
Description
The MT2A (metallothionein 2A) is a protein-coding gene located on chromosome 16.
MT2A, encoded by the MT2A gene, is a metallothionein protein. A single-nucleotide polymorphism (rs28366003) in MT2A, replacing adenine with guanine, has been linked to various cancers and chronic diseases. MT2A has been shown to interact with protein kinase D1.
Metallothioneins, like MT2A, contain a high concentration of cysteine residues. These residues bind to various heavy metals. The expression of these proteins is controlled by both heavy metals and glucocorticoids.
MT2A is also known as MT-2, MT-II, MT2.
