MRPL45
Description
The MRPL45 (mitochondrial ribosomal protein L45) is a protein-coding gene located on chromosome 17.
MRPL45 is a human gene that encodes a protein known as mitochondrial ribosomal protein L45. This protein is a component of the mitochondrial ribosome, the organelle responsible for protein synthesis within mitochondria. Mitochondrial ribosomes are distinct from the ribosomes found in the cytoplasm of cells. MRPL45 is essential for the proper assembly and function of the mitochondrial ribosome, and ultimately for the production of proteins essential for cellular respiration and energy production. Mutations in MRPL45 can lead to mitochondrial dysfunction and various health problems.
MRPL45 is a component of the mitochondrial ribosome, specifically the large subunit (39S). It is essential for the synthesis of mitochondrial proteins, which are crucial for cellular respiration and energy production. The precise role of MRPL45 within the ribosome is still under investigation, but it is believed to contribute to the structural integrity and/or function of the ribosome.
MRPL45 is also known as L45mt, MRP-L45, Mba1, mL45.