MROH5
Description
The MROH5 (maestro heat like repeat family member 5 (gene/pseudogene)) is a protein-coding gene located on chromosome 8.
MROH5 (Mitochondrial Rhodanese-Like Protein 5) is a human gene that encodes a mitochondrial protein involved in the biosynthesis of heme, a vital molecule for oxygen transport and cellular respiration.
MROH5 is a mitochondrial protein that is involved in the synthesis of heme, a molecule essential for oxygen transport and cellular respiration. It catalyzes the oxidation of protoporphyrin IX to protoporphyrin IX monomethyl ether, a key step in the heme biosynthesis pathway. Mutations in MROH5 can lead to erythropoietic protoporphyria (EPP), a rare genetic disorder characterized by photosensitivity and accumulation of protoporphyrin IX in erythrocytes.
MROH5 is also known as -.
