MRM1
Description
The MRM1 (mitochondrial rRNA methyltransferase 1) is a protein-coding gene located on chromosome 17.
MRM1 refers to a human gene that encodes a mitochondrial rRNA methyltransferase, specifically involved in modifying the 16S rRNA.
MRM1 is an S-adenosyl-L-methionine-dependent enzyme that catalyzes the addition of a methyl group to the 2'-hydroxyl group of guanosine at position 1145 (Gm1145) within the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA). This modification, known as 2'-O-methylguanosine, is critical for the proper function of the peptidyl transferase domain of the mtLSU rRNA, a region essential for protein synthesis within mitochondria.
MRM1 is also known as -.
