MON2
Description
The MON2 (MON2 homolog, regulator of endosome-to-Golgi trafficking) is a protein-coding gene located on chromosome 12.
The MON2 gene in humans codes for the MON2 protein homolog, which plays a role in regulating membrane trafficking of cargo proteins.
MON2 protein is involved in regulating the movement of cargo proteins within cells. It collaborates with ATP9A and DOP1B to control the sorting of WLS protein away from degradation in lysosomes, a process mediated by the SNX3 retromer complex.
MON2 is also known as -.
Associated Diseases
- lysosomal storage disease
- Griscelli syndrome type 3
- uncombable hair syndrome
- oculocutaneous albinism type 3
- hypotrichosis simplex
- ermine phenotype
- Tietz syndrome
- Waardenburg syndrome, IIa 2F
