MIR4761
Description
The MIR4761 (microRNA 4761) is a ncRNA gene located on chromosome 22.
MicroRNA 4761 (miR-4761) is a small, non-coding RNA molecule involved in regulating gene expression. It is encoded by the MIR4761 gene in humans. miRNAs like miR-4761 play a critical role in post-transcriptional regulation, influencing the stability and translation of messenger RNA (mRNA) molecules. The process begins with the transcription of the MIR4761 gene, producing a precursor miRNA (pri-miRNA). This precursor is then processed by enzymes, Drosha and Dicer, to generate the mature miR-4761. The mature miRNA is incorporated into a complex called the RNA-induced silencing complex (RISC). RISC binds to target mRNAs through imperfect base pairing, leading to either translational inhibition or destabilization of the mRNA, effectively controlling gene expression. The RefSeq represents the predicted microRNA stem-loop.
MIR4761 is a human microRNA gene that encodes a small non-coding RNA molecule, microRNA 4761 (miR-4761). This miRNA plays a crucial role in regulating gene expression at the post-transcriptional level. Specifically, miR-4761 interacts with messenger RNA (mRNA) molecules, leading to either suppression of their translation into proteins or degradation of the mRNA itself. This regulatory mechanism involves a series of steps: First, miR-4761 is transcribed from the MIR4761 gene as a longer precursor molecule (pri-miRNA). This precursor is then processed by enzymes called Drosha and Dicer to generate the mature miR-4761. The mature miR-4761 is incorporated into a complex called the RNA-induced silencing complex (RISC), which binds to specific target mRNAs. This binding can result in either the inhibition of protein synthesis from the target mRNA or the destruction of the mRNA itself. The exact target mRNAs and biological functions regulated by miR-4761 are still being investigated.
MIR4761 is also known as -.
