MIR124-1
Description
The MIR124-1 (microRNA 124-1) is a ncRNA gene located on chromosome 8.
miR-124-1 is a microRNA that is highly expressed in the brain and plays a key role in neuronal development and function. It regulates gene expression by binding to messenger RNA (mRNA) and inhibiting its translation. miR-124-1 promotes neuronal differentiation by repressing the expression of non-neuronal genes and activating the expression of neuronal genes. It is also involved in synapse formation and plasticity. miR-124-1 has been implicated in various neurological disorders, including Alzheimer‘s disease, Parkinson‘s disease, and autism spectrum disorder.
miR-124 is a brain-enriched microRNA that plays a crucial role in neuronal development and function. It regulates the expression of a wide range of genes involved in neuronal differentiation, synapse formation, and plasticity. miR-124 promotes neuronal differentiation by repressing the expression of non-neuronal genes and activating the expression of neuronal genes. It also contributes to synapse formation and plasticity by regulating the expression of genes involved in these processes. In addition to its role in neuronal development, miR-124 has been implicated in various neurological disorders, including Alzheimer‘s disease, Parkinson‘s disease, and autism spectrum disorder. It has also been shown to have a role in glioblastoma, a type of brain cancer.
MIR124-1 is also known as MIR124A, MIR124A1, MIRN124-1, MIRN124A1, mir-124-1.