MIAT
Description
The MIAT (myocardial infarction associated transcript) is a ncRNA gene located on chromosome 22.
MIAT, also known as nuclear paraspeckle assembly transcript 1 (NEAT1), is a long non-coding RNA (lncRNA) found in the nucleus of human cells.
MIAT, also known as nuclear paraspeckle assembly transcript 1 (NEAT1), is a long non-coding RNA (lncRNA) that plays a crucial role in the formation and function of nuclear paraspeckles. These nuclear bodies are involved in various cellular processes, including gene regulation, mRNA processing, and response to stress. MIAT is believed to act as a scaffold for the assembly of paraspeckles, interacting with proteins and other RNAs to modulate their activity. It has been implicated in diverse biological pathways, including cell growth, development, and disease.
MIAT is also known as C22orf35, GOMAFU, LINC00066, NCRNA00066, RNCR2, lncRNA-MIAT.
Associated Diseases
- Miyoshi myopathy
- breast cancer
- Mobius syndrome
- in situ carcinoma
- schizophrenia 15
- type 2 diabetes mellitus
- Phelan-McDermid syndrome
- glycogen storage disease due to glycogen branching enzyme deficiency
- FRAXE intellectual disability
- Potocki-Lupski syndrome
