GABBR2

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GABBR2: A Key Player in Neurology and Psychiatry

Description

GABBR2 (gamma-aminobutyric acid (B) receptor subunit 2) is a protein that plays a crucial role in the brain's inhibitory neurotransmission system. It is a subunit of the GABAB receptor, which is responsible for mediating the effects of the inhibitory neurotransmitter GABA. GABA is involved in a wide range of brain functions, including synaptic plasticity, cognition, and mood regulation.

Associated Diseases

Mutations in GABBR2 have been linked to a number of neurological and psychiatric disorders, including:

• Epilepsy
• Autism spectrum disorder
• Intellectual disability
• Anxiety disorders
• Depression
• Schizophrenia

Did you Know ?

Approximately 1% of individuals with epilepsy have a mutation in GABBR2.