EFNA4


Description

The EFNA4 (ephrin A4) is a protein-coding gene located on chromosome 1.

Ephrin A4 is a protein encoded by the EFNA4 gene in humans. It belongs to the ephrin (EPH) family, a large subfamily of receptor protein-tyrosine kinases involved in developmental processes, particularly in the nervous system and erythropoiesis. Ephrins are classified into two groups based on their structure and sequence: ephrin-A (EFNA) and ephrin-B (EFNB). EFNA class ephrins, like Ephrin A4, are anchored to the membrane by a glycosylphosphatidylinositol linkage. The EFNA4 gene encodes three transcript variants that produce distinct proteins.

EFNA4 is also known as EFL4, EPLG4, LERK-4, LERK4.

Associated Diseases


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