WDR4

Description

The WDR4 gene, encodes a protein known as WD repeat-containing protein 4. This protein plays a crucial role in various cellular functions, including protein degradation, cell cycle regulation, and DNA repair. WDR4 is involved in the formation of protein complexes, interacting with other proteins to modulate their activity. Understanding the function of WDR4 is essential for comprehending how cells maintain their integrity and respond to stress.

Associated Diseases

• Neurodevelopmental disorders (e.g., intellectual disability, autism spectrum disorder)
• Cancer (e.g., leukemia, lymphoma)
• Cardiovascular diseases (e.g., heart failure)

Did you know?

Mutations in WDR4 are associated with a rare genetic disorder known as WDR4-associated intellectual disability syndrome.