UQCRQ
Description
The UQCRQ (ubiquinol-cytochrome c reductase complex III subunit VII) is a protein-coding gene located on chromosome 5.
UQCRQ, also known as Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa, is a protein encoded by the UQCRQ gene. It is a component of Complex III, a key player in the mitochondrial electron transport chain. Mutations in UQCRQ can lead to serious neurological disorders. This protein can be modified by infection with Trypanosoma cruzi, which can affect heart muscle tissue. UQCRQ is a transmembrane protein located on chromosome 5, spanning 2,217 base pairs and producing an 82 amino acid protein with a molecular weight of 9.9 kDa.
UQCRQ, also known as Complex III subunit VIII, plays a crucial role in the electron transport chain within mitochondria. It is a subunit of ubiquinol-cytochrome c oxidoreductase, also known as Complex III, a multi-protein complex involved in oxidative phosphorylation. Complex III facilitates the transfer of electrons from ubiquinol to cytochrome c, a key step in the process of generating energy from food. This electron transfer is coupled to the movement of protons across the mitochondrial membrane, generating a proton gradient that is utilized by ATP synthase to produce ATP, the primary energy currency of cells.
UQCRQ is also known as MC3DN4, QCR8, QP-C, QPC, UQCR7.
