TFR2 : transferrin receptor 2
Description
TFR2 (Transferrin Receptor 2) is a protein that plays a crucial role in iron regulation. It acts as a receptor for transferrin, a protein that transports iron in the bloodstream. TFR2 helps cells absorb iron by binding to transferrin and triggering its uptake. This process is essential for maintaining normal iron levels in the body. TFR2 is primarily expressed in the liver, where it regulates the production of hepcidin, a hormone that controls iron absorption in the intestines. TFR2‘s role in iron homeostasis makes it a critical factor in various physiological processes, including red blood cell production, DNA synthesis, and energy metabolism.
Associated Diseases
Did you know?
TFR2 is a promising target for developing new therapies for iron disorders.
